4168 Understanding ECM-Based Drug Resistivity in Breast Cancer

OBJECTIVES/GOALS: Cell-cell (CC) and cell-matrix interactions (CM) are known to affect drug sensitivity of cancer cells, but are not effectively recapitulated using 2D platforms.This research aims to determine how cell and matrix interactions confer drug resistivity in 3 distinct culturing models: 2D (no CM/limited CC), 3D spheroids (CC) and 3D fib

read more

Clinicopathologic and radiographic features in 33 cats with aspiration and 26 cats with bronchopneumonia (2007‐2017)

Abstract Background Aspiration pneumonia (AP) and bronchopneumonia (BP) are poorly characterized diseases in cats that share clinical similarities to inflammatory airway disease (IAD).Objectives Describe clinicopathologic, radiographic, and microbiologic features in cats with AP and BP and compare findings to those in cats with IAD.Animals Thirty?t

read more

Short-Term Statistical Forecasts of COVID-19 Infections in India

COVID-19 cases in India have been steadily increasing since January 30, 2020 and have led to a government-imposed lockdown across the country to curtail community transmission with significant impacts on societal systems.Forecasts using mathematical-epidemiological models have played and continue to play an important role in assessing the probabili

read more